PASSIVE TRANSFER OF TOLERANCE TO PYROGENICITY OF BACTERIAL ENDOTOXIN
نویسندگان
چکیده
منابع مشابه
Passive Transfer of Tolerance to Pyrogenicity of Bacterial Endotoxin
The typical febrile response of normal rabbits given bacterial endotoxin intravenously may be modified by prior administration of plasma or, less effectively, serum of endotoxin-tolerant donors. This altered response is characterized by disappearance of the second rise in fever and by a striking reduction in fever index. It thus resembles the course of fever shown by rabbits made tolerant to en...
متن کاملFurther Studies on Passive Transfer of Tolerance to Pyrogenicity of Bacterial Endotoxin
The effect of various schedules for inducing tolerance to bacterial endotoxin in donor rabbits upon suitability for demonstration of passive transfer of tolerance to pyrogenicity in normal recipients has been investigated. Long-term treatment of donors, through 5 weeks, is no more effective than a brief series of injections, adding further evidence that tolerance is not attributable to specific...
متن کاملCompartmentalization of tolerance to endotoxin.
BACKGROUND Tolerance to endotoxin has been defined and analyzed either entirely in vivo or entirely in vitro. In contrast, the hyporeactivity of circulating leukocytes reported in patients with sepsis, and often referred to as the phenomenon of tolerance to endotoxin, is an ex vivo observation. Therefore, our objective was to set up an ex vivo model of tolerance to endotoxin. METHODS Mice wer...
متن کاملinvestigating the relationship between ambiguity tolerance and willingness to translate of iranian prospective english translators: an sem revalidation study
cognitive studies of translation process have recently been awarded a great deal of attention. there exists a psychological angle to almost all translation activities. the present study, thus, deals with analysing the relationships between iranian prospective translators tolerance for ambiguity (ta) and their willingness to translate (wtt). the research was conducted as a mixed methods study, d...
Mechanisms of Endotoxin Tolerance
Healthy male volunteers were rendered tolerant to the pyrogenic and toxic activities of bacterial endotoxin by daily intravenous injections. Five subjects were given 0.5 microg Salmonella typhosa endotoxin for 7 days; four subjects were given Pseudomonas endotoxin, increasing over a period of 30 days from 25 to 250 microg. Reticuloendothelial system (RES) phagocytic activity was assessed by ser...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1960
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.111.4.453